Since 2006, Oligo Factory has specialized in producing custom DNA and RNA oligonucleotides with a delivery scale of 25mg up to the kilogram range.
Our solid-phase synthesis approach provides outstanding quality and purity for oligos with 200 bases or fewer. With our 100% US-based primary supply chain, we have shipped in six weeks or less every single order since January 2022.
TIP: for oligos of 80 bases or fewer, 25mg is usually at least 1 umol of material
What We Build
We’ve synthesized oligos with almost every modification.
For more information on our exotic modifications, click here.
Synthesis & Purification
Proprietary Synthesis Technology
Our third-generation in-house built solid-phase oligo synthesizer runs twice as fast as commercially-available synthesizers, provides outstanding initial purity, and is designed to work most efficiently at scale.
Our purification team uses several industry approved purifications via HPLC – both reverse-phase and ion-exchange. We also can develop in-house options per customer requirement to maximize yield and purity needs. Our standard purity delivered is 85%+ as measured by HPLC, but we can comfortably provide purities of 90%+, 95%+, or higher as needed.