Custom Oligos

Oligo Factory:
Custom DNA & RNA Oligonucleotide Synthesis

Fast, high-quality oligo synthesis for therapeutic, diagnostic, and other demanding applications

Streamlined, Custom Oligonucleotide Production: Quality Meets Speed

Quality Systems: RUO, GMP, and ISO13485
Turnaround Time: Production to delivery in ~4-6 weeks
Scalability: mgs to kg yields support late-stage discovery through clinical trials

Therapeutics

Our outstanding turnaround time and delivery at-scale, without sacrificing quality, enables therapeutics manufacturers to get to market fast.

CRISPR, gRNA
siRNA, dsiRNA
ASO
Aptamers

Life Science Tools

Our scalable, high quality production enables tool providers to lower their costs and produce reliable results.

Molecular Diagnostics
qPCR
NGS

Additional Applications

With nearly two decades in business, we have supported a wide variety of novel applications.

Agriculture
Industrial
Purification

Examples of oligos that we make:

We offer almost any commercially available modification as well as custom modifications. Click here to see a list of commonly used mods.

Antisense Oligonucleotides

Single-stranded RNA or DNA for targeted therapies and gene silencing

siRNA & miRNA

Double-stranded RNA or chimeric molecules for gene silencing and expression modulation

Aptamers

Aptamers are oligonucleotides that are designed to bind tightly to protein targets in therapeutic and diagnostic applications.

Guide RNAs

For RUO or therapeutic applications, guide RNAs are a key component of CRISPR-based gene editing workflows

Primers and NGS Adapters

PCR primers, P5, P7 and other sequencing adapters

Fluorescent Probes

Single or dual-labeled probes are available with all common fluors and quenchers

We deliver outstanding customer service:

01

Custom Sequence Submission

Submit your sequence through our simple online portal.

02

Personalized Consultation

A scientist assigned to work with you directly throughout your order will schedule a time with you to discuss your custom order.

03

Order
Finalization

After your consultation, we will finalize your order and immediately begin production.

04

Production & Delivery

Your oligo will be produced entirely in-house by our expert team utilizing our proprietary oligo synthesis technology.

05

Post-Delivery Consultation

After your custom oligo order is delivered, your Oligo Factory scientist will check in to ensure everything worked out as expected.

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about oligo factory

Founded in 2006 by oligo synthesis technology experts, our goal is to provide custom DNA and RNA oligo synthesis at scale – mgs to kgs – to life science customers.

The Oligo Factory team is made up of skilled chromatographers, synthesis chemists, instrumentation engineers and commercialization specialists with more than 60 years of combined experience.

Customer satisfaction is in our DNA. We are committed to providing high-quality oligos to customer specifications and exceptional customer service.

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Why customers love Oligo Factory:

High Purity Oligos: 80% to >95% purity based on customer specifications
Unrivaled Speed: Production to delivery with 4-6 weeks
Scale For Growth: 25 mgs to kilograms of oligos, delivered on-spec and on-time
Customized Quality Offerings: RUO, GMP-like, and GMP production is available
Experienced Scientists: 18 years experience in custom oligo synthesis