Oligonucleotide Probes
Essential Tools for Molecular Detection
OVERVIEW
Illuminating Molecular Interactions
Probes are oligonucleotides designed to detect specific DNA or RNA sequences and play a central role in various molecular biology techniques, such as fluorescence in situ hybridization (FISH), quantitative PCR (qPCR), next-generation sequencing (NGS), molecular diagnostics, and gene expression analysis. Probes must be carefully designed and manufactured to maximize signal-to-noise ratios and avoid off-target binding, enabling researchers to visualize and quantify target molecules with high sensitivity and specificity.
Oligo Factory leverages its proprietary NANDA Series synthesis platform to rapidly and consistently produce high-quality probes with exceptional purity and yield. Our advanced technology enables precise control over complex modifications, ensuring reliable results for even the most demanding applications.
Discover how Oligo Factory’s approach delivers high-quality, custom dual dye labelled DNA probes with rapid turnaround times while maintaining cost efficiency in this case study.
Benefits
The Oligo Factory Advantage
At Oligo Factory, we specialize in synthesizing high-quality, custom probes that deliver reliable performance.
- Proprietary synthesis technology: Our NANDA Series synthesizers enable multiple monitoring modes (colorimetric, gravimetric, and conductivity) for precise manufacturing control.
- Expertise in modifications: We excel in incorporating a wide range of fluorescent labels (e.g., FAM, ROX, Cy3, Cy5, Alexa Fluor dyes), quenchers (e.g., BHQ, iQuench), minor groove binders (MGBs), spacers, and linkers.
- Superior Performance: Our closed-system single oligonucleotide synthesis workflow ensures high purity and batch-to-batch consistency.
- Quality compliance: We are ISO 9001:2015 and ISO 13485:2016 certified ensuring quality production and monitoring through our validated QMS.
Applications
Powering Innovation
Our custom probes are at the core of cutting-edge research, diagnostics, and life science applications.
- Cancer biomarker detection
- Pathogen identification in clinical diagnostics
- Chromosomal and cellular localization studies
- NGS library preparation and target enrichment
- Real-time monitoring of gene expression
Why Life Science Companies Partner
with Oligo Factory
Expert Support
With over 15 years of experience, our dedicated scientists work with you to design probes tailored and optimized to your specific application.
Scalable Production
Flexible production capabilities, from milligram to kilogram quantities, streamline the transition from discovery to commercialization.
Rapid Delivery
With a maximum order turnaround time of six weeks, you receive the probes you need to expedite your timelines.
Ready to elevate your molecular detection capabilities?
Address:
56 Boynton Rd, Holliston, MA 01746
Contact:
Phone: (508) 275-3561
Email: Info@oligofactory.com
