Diagnostics
CRISPR-based Gene Editing
Guide RNA (gRNA) for Precision Medicine Development
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Overview
gRNA is a key component of the CRISPR-Cas9 gene editing technology.
As short oligonucleotides, they are responsible for directing the Cas9 enzyme to specific DNA sequences for targeted gene knockouts, insertions, replacements, base editing, and epigenetic modulation. As CRISPR applications in disease modeling and precision medicine expand, high-quality gRNA production becomes increasingly important to optimize stability and delivery in complex biological systems and minimize off-target edits.
Oligo Factory leverages finely tuned solid phase synthetic chemistry to produce high-quality gRNA from microgram to hundreds of grams quantities. Our NANDA Series synthesizers enable precise control and enhanced purity for even the most complex gRNA sequences.
Use Cases
Facilitating Breakthroughs
Our high quality gRNA support successful CRISPR gene editing.
- Genome-wide screening for target identification
- Cancer immunotherapy research
- infectious disease modeling
- Functional genomics studies
